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What are Formalin-Fixed Paraffin-Embedded Tissues?

Formalin-Fixed Paraffin-Embedded Tissues (FFPE) are specimens that have been treated with formalin to fix the tissue and then embedded in paraffin. This treatment makes the tissue durable and resistant to decay. 

FFPE block storage can be used for a variety of studies, including histopathology, immunohistochemistry, electron microscopy, and cytology.

Benefits of having a formalin-fixed, paraffin-embedded specimen

Formalin-fixed, paraffin-embedded specimens provide many advantages over traditional fixed tissue specimens. These advantages include: 

They are transparent and easily viewed under a microscope.

They remain relatively unchanged after being fixed and can be used for long-term storage.

They are less likely to fragment or decay over time.

How to store Formalin-Fixed, Paraffin-Embedded Specimens

Formalin-Fixed, Paraffin-Embedded Specimens are a valuable and important part of the pathology. They can be stored in many ways, but the most common way is to store them in formalin. Formalin is a strong compound that will preserve the specimen for a long time. 

The paraffin will help to protect the tissue from damage. There are many types of formalin-fixed, paraffin-embedded specimens, but this brief introduction will focus on two of the most common.

The first type of formalin-fixed, paraffin-embedded specimen is known as a frozen section. This type of specimen is prepared by freezing the tissue in liquid form and then embedding it in paraffin. Frozen sections can be used for many different types of examinations, including microscopy and histopathology.

The second type of formalin-fixed, paraffin-embedded specimen is called an immunohistochemistry stain. This type of specimen is prepared by embedding the tissue in paraffin and then staining it with antibodies specific to a particular antigen.